2022 German ethnologist, researcher and author Christian Rätsch dies at the age of 65. *** The latest amendment to the New Psychoactive Substances Act (NpSG) in Germany has gone very wrong. A punctuation error in the legal text leads to a number of LSD derivatives being subsequently legalized or not being recorded. *** The use of 1V-LSD and other psychedelics catches on in club culture. *** The Netflix documentary series ‚How to Change Your Mind‘ presents Albert Hofmann’s groundbreaking pioneering work with LSD to an international audience. *** Awareness Lectures on Psychedelics in Switzerland (ALPS) conference convenes in Switzerland. *** Drug manufacturers invest in research into pychedelics. The New York biotech company MindMed announces that the first patient is being treated with LSD in a clinical trial for the treatment of generalized anxiety disorder. *** The ‚Drug Culture‘ congress takes place in Leipzig for the first time. *** A demonstration in front of the headquarters of the US Drug Enforcement Administration (DEA) in Virginia leads to the arrest of 16 psychedelic activists.