1964 Publication of the `Psychedelic Experience: A Manual Based on the Tibetan Book of the Dead` by Leary, Metzner & Alpert, which has never been out of print. *** Leary`s group establishes an LSD cultural research center called Castalia Foundation on the Hichcock estate in Milbrook, New York, and develops the `experimental typewriter` for a meta-communication during the LSD plateau. *** John C. Lilly experiments in the Virgin Islands giving LSD to dolphins and taking it in the samahdi- or isolation tank, which he developed. *** Alexander (Sasha) Shulgin synthesizes DOM, a strong, long-lasting psychedelic. *** Psychedelic Information Centers spring up in Cambridge, Washington DC and elsewhere.