1943 (April 16th) Dr. Hofmann experiences `a peculiar presentiment` that LSD-25 might well be valuable as a circulatory or respiratory stimulant and decides intuitively to re-synthesize this compound. (April 16) Performing with LSD-25 at his Sandoz laboratory, Hofmann accidentally absorbs a miniscule amount of the substance through the skin of his finger. The amount is probably equal to a dose of 50 micrograms. He experiences `a strange inebriation … a kaleidoscopic play of colors` that lasted 3-4 hours.